In mammalian organisms liquid tumors such as acute myeloid leukemia (AML) are related to spontaneous chromosomal translocations ensuing in gene fusions.We previously developed a system named bridge-induced translocation (BIT) that allows linking together two different chromosomes exploiting the strong endogenous homologous recombination system of t
Harvester : an edge service harvesting heterogeneous resources for ATLAS
The Production and Distributed Analysis (PanDA) skylight quilt pattern system has been successfully used in the ATLAS experiment as a data-driven workload management system.The PanDA system has proven to be capable of operating at the Large Hadron Collider data processing scale over the last decade including the Run 1 and Run 2 data taking periods.
Aging causes a reorganization of cortical and spinal control of posture
Classical studies in animal preparations suggest a strong role for spinal control of posture.In young adults it is now established that the cerebral cortex contributes to postural control jean louis sanchet of unperturbed and perturbed standing.The age-related degeneration and accompanying functional changes in the brain, reported so far mainly in
A peep into the transcriptome studies of the industrially important brown algae with special focus on Macrocystis genus
Brown algae are a commercial source of different polysaccharides/hydrocolloids that has been used to produce food, pharmaceutical, tenga air-tech regular and several other useful biotechnological stuff.Nevertheless, transcriptomics has become a tool that not only provides valuable information for the understanding of the diamondbacks retro hat phys
AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles
Summary: The autophagy pathway is an essential facet of the innate immune response, capable of rapidly targeting intracellular bacteria.However, the initial signaling regulating autophagy induction in response to pathogens remains largely unclear.Here, we report that AMPK, an upstream activator of the autophagy pathway, is stimulated upon detection